Mitochondria

It is estimated that 85% of the oxygen contained in every breath you take is consumed by the mitochondria within each cell of your body.1 The decay of these energy-producing powerhouses in turn lies at the core of most age-related pathologies.

Back in 1983, when coenzyme Q10 was first introduced, the only concern was being able to afford it. A 100-count bottle of 10 mg CoQ10 capsules retailed for almost $100 in today’s dollars. CoQ10 prices plummeted as more companies began producing it. In 1995, Life Extension® introduced an oil-soluble CoQ10 for greater absorption into the blood.

Findings just released at the 5th Annual International CoQ10 Symposium (November 9-12, 2007, in Kobe, Japan) show ubiquinol to be remarkably beneficial in those with advanced-stage cardiac disorders. Conventional CoQ10 (ubiquinone), on the other hand, was not adequately absorbed in these cardiac patients. According to the researchers, patients with severe heart failure have difficulty assimilating ubiquinone into their bloodstream, whereas ubiquinol readily absorbs and displays greater...

In 1983, Life Extension® introduced a relatively little-known compound called coenzyme Q10. Our review of the literature back then had unearthed data confirming its power to boost the health and energy output of the mitochondria. Today, scientists recognize mitochondrial dysfunction as a key biomarker of aging. To take one instance, researchers have recorded evidence of 50% more mitochondrial damage in the brain cells of humans over 70 compared to middle-aged individuals.

Go to Google and enter “mitochondria” and “neurodegeneration.” You’ll find hundreds of published studies linking the two. The decay of mitochondria in brain cells is a primary cause of all neurodegenerative disorders, from Parkinson’s to dementia.

Given the rising epidemic of diabetes and its devastating complications, natural strategies that support healthy blood sugar (glucose) and protect against oxidative stress offer hope for many individuals. Metabolic syndrome—a combination of risk factors such as insulin resistance, high blood pressure, high triglycerides, and low high-density lipoprotein (HDL)—increases one’s risk for diabetes and cardiovascular disease.

Mounting evidence documents the ability of carnosine to prevent many of the detrimental effects of aging. In our youth, carnosine shields us from the onslaught of oxidation, glycation, DNA damage, and other reactions that injure tissues and cripple organs.

Our society has been programmed to believe that complex medical problems can be fixed with simple solutions. Everyone reading this article has probably seen thousands of TV commercials promoting immediate relief from arthritis pain by taking the right brand of aspirin, ibuprofen, acetaminophen, or naproxen.

Do you ever wish you could just recharge your batteries? Most of us do, especially as we grow older. Fatigue is a major problem in American adults, accounting for millions of office visits each year. The complaints are similar: groggy for much of the morning, can’t sleep well or long enough at night, lack the energy for daily tasks and even enjoyable diversions.

Burnout is real. In May 2019, the World Health Organization officially included it in its International Classification of Diseases. This recognition confirmed that burnout was not a figment of the imagination, or something suffered only by “weak” or “unmotivated” people.1 Medical treatments are limited. The Mayo Clinic recommends sleep and relaxation.2 But now there’s hope for the 30% to 72% of working people who suffer from burnout syndrome.3,4

In year 2001, Life Extension® researchers actively sought a method to boost levels of a coenzyme in aging people. We knew this was critical to achieving healthy longevity. Consumers had to wait until 2014 for a validated method to become available. This coenzyme is called NAD+ and is vital for energizing cells and supporting youthful cellular processes.

Life Extension® receives many inquiries about stem cell infusion therapies offered in the United States and other countries. Our current view from small human trials is that there may be a benefit to infusions of exosomes that are naturally secreted from healthy stem cells. Stem cell exosomes have regenerative properties that help restore functional cells needed to maintain tissue and organ viability. Overlooked when considering exosome treatments is the ability to rejuvenate existing stem...